Anti tuberculosis drugs pdf

 

 

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Anti-tuberculosis drugs have widely variable pharmacokinetic characteristics but as they work efficiently together, it is unnecessary to match these when giving drug combinations. The effects of drug-drug interactions are usually small though the interactions with Table 2. Drug Regimens for Microbiologically Confirmed Pulmonary Tuberculosis Caused by Drug-Susceptible Organisms. Intensive Phase. Anti-infectives. Hormone therapy Narcotics Anticoagulants Immunosuppressive. agents Anticonvulsants Cardiovascular agents. Figure 5: Tuberculosis drug resistance patterns as a percentage of isolates tested, 2005 to 2015. Table 1: Critical concentrations for routine Table 5: Results for routine drug susceptibility testing of Mycobacterium tuberculosis complex isolates to anti-tuberculosis drugs for Alberta, 2005 to 2015. Most anti-tuberculosis drugs kill bacteria while it is dividing, which explains why more time is needed to kill the slow growth population of bacteria (Table 1). (2003) Incidence of serious side effects from first line antituberculosis drugs among patients treated for active tuberculosis. people with presumed drug-sensitive tuberculosis (TB) who cannot take standard rst-line drugs. • Cause additional adverse drug reactions, such as musculoskeletal damage, gastrointestinal including uoroquinolones anti-tuberculosis drugs for rifampicin resistant pulmonary tuberculosis. Keywords: Tolerability of Anti-TB Drugs; toxicity; Side Effects; Chemotherapy of Tuberculosis; Hepatoprotector. One of the main reasons for the insufficient effectiveness of tuberculosis chemotherapy, along with the increasing drug resistance of the pathogen and low patient compliance Extra-pulmonary TB is more common in patients with chronic renal disease when compared to those with normal renal function. 9. All but first line drugs must only be used after discussion with a consultant physician experienced in treating TB or with a Regional Tuberculosis Control Centre.

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